Although anemia is recognized as a frequent, possibly constant, feature of the cachexia of late syphilis, a general exposition of the blood disorders due to this infection is not readily available. As Eason1 remarked, there has been little change in view in the quarter century regarding the anemia of syphilis, while our conception of aortitis has changed greatly.
In this communication, my purpose is to present a brief review of the present opinion as it may be gleaned from the literature, at the same time reporting certain personal observations:
Fournier distinguished the following types: (1) simple anemia, characterized by a diminution in the number of red cells and a proportional reduction in the hemoglobin; (2) chlorotic anemia, with a greater reduction in the hemoglobin than in the red cells; (3) chlorotic anemia with leukocytosis; (4) anemia of pernicious type, and (5) leukemic type. The first three types were evidently
CUMMER CL. ANEMIA AND OTHER BLOOD CHANGES IN SYPHILIS. JAMA. 1928;91(10):689-695. doi:10.1001/jama.1928.02700100001001