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February 6, 1943


Author Affiliations


From the Department of Dermatology and Syphilology of the Western Reserve University School of Medicine and the University Hospitals.

JAMA. 1943;121(6):413-420. doi:10.1001/jama.1943.02840060031008

This report is based on a clinical study of 60 cases of cutaneous melanoma. Thirty-five were seen in private practice and 25 are from records of the departments of dermatology and syphilology and of surgery of the University Hospitals and represents all of the patients between the years 1921 and 1941, a period of twenty years.

In the treatment of few pathologic conditions is there such pessimism and divergence of opinion as in that of cutaneous melanoma. This is due to the generally confused ideas of the average physician concerning pigmented moles and their relation to malignant growths, the highly malignant nature of melanomas, their tendency to metastasize early and the generally unsatisfactory results obtained from various treatment procedures. Nevertheless, it is true that lack of diagnostic skill and delay in the institution of adequate treatment have many times contributed to the poor results.

PRECURSOR LESIONS  The great majority of

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