The subject of mental disturbances associated with pituitary disorders embraces two large fields—psychiatry and endocrinology—in either of which any discussion is considerably influenced by the subjective interpretative point of view. Both fields present unlimited opportunity for fanciful speculation and interpretive mysticism. For such a study as is here proposed, the use of the experimental method is possible to only a very limited extent, and we must content ourselves with such clinical material as nature provides.
The psychiatrist, from necessity, must be interested in a general and total view of all the symptoms of the sick man. He well recognizes his limitations in estimating the etiologic importance of the multitudinous factors in the causation of mental disorder. Particularly is this true of somatic disorders outside the central nervous system. Similarly, conservative endocrinologists are hesitant in discussing with finality interglandular relationships, and in ascribing to glandular disease other changes that have taken
MENNINGER WC. THE MENTAL DISTURBANCES ASSOCIATED WITH PITUITARY DISORDERS. JAMA. 1928;91(13):951-955. doi:10.1001/jama.1928.02700130029008