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Comment & Response
February 14, 2017

Oxygen Supplementation Among Patients in the Intensive Care Unit

Author Affiliations
  • 1Department of Intensive Care, Vrije Universiteit Medical Center, Amsterdam, the Netherlands
JAMA. 2017;317(6):646-647. doi:10.1001/jama.2016.20826

To the Editor In the randomized clinical trial among critically ill patients comparing conservative (partial arterial oxygen pressure [Pao2] of 70-100 mm Hg or arterial oxyhemoglobin saturation [Spo2] of 94%-98%) with conventional (Pao2 of<150 mm Hg or Spo2 of 97%-100%) oxygen therapy, Dr Girardis and colleagues1 observed an absolute decrease in intensive care unit (ICU) mortality of 8.6% in the conservative vs conventional therapy groups. The study has several shortcomings.

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