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October 27, 1928

STUDIES IN THE DIGESTION OF LECITHIN BY PANCREATIC ENZYMES

Author Affiliations

CHICAGO

From the John McCormick Institute for Infectious Diseases and the Cook County Hospital.

JAMA. 1928;91(17):1248-1250. doi:10.1001/jama.1928.02700170012004
Abstract

A review of the literature reveals that in 1898 Deucher1 studied the metabolism in three cases of obstruction of the pancreatic duct, two by carcinoma and one by cicatricial occlusion from duodenal ulcer, and found that, on a diet composed mostly of milk and eggs, a large amount of lecithin was recovered from the stool. Salomon2 in 1902 reported similar observations and again in 1908 confirmed Deucher's work. Ehrmann,3 in 1909-1910, studied the stools of a patient suffering from chronic pancreatitis and found increased lecithin excretion. The same author4 in 1912 again found conclusive evidence that there was a large amount of lecithin excreted in two cases of obstruction of the pancreatic duct. Schumacher,5 on investigating the stainability of lecithin, found, in agreement with earlier histochemical observations, that the fuchsin series are the best stains for lipoids, victoria blue being the finest. He found that

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