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News From the Food and Drug Administration
March 7, 2017

Relief for Chronic Constipation

JAMA. 2017;317(9):900. doi:10.1001/jama.2017.1065

A new medication for adults with chronic idiopathic constipation has received FDA approval.

Plecanatide, marketed as Trulance, is a guanylate cyclase-C agonist that stimulates intestinal fluid secretion and accelerates stool passage. The drug is not recommended for children younger than 6 years because it may cause diarrhea and potentially serious dehydration.

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