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April 10, 1943

IRRADIATION OF THE SPLEEN AND PITUITARY FOR CONTROL OF PUBERAL BLEEDINGBIRTH OF A NORMAL CHILD FOLLOWING TREATMENT OF THE MOTHER

JAMA. 1943;121(15):1199-1201. doi:10.1001/jama.1943.02840150013004
Abstract

An entirely unwarranted fear that irradiation may do harm to the generative organs is one of the main reasons why this well tested method is not more generally utilized in the treatment of irregular bleedings in young girls. While it is true, as Halberstaedter1 reported early after the advent of x-rays, that these exercise a selective action on the ovaries, nevertheless, when roentgen therapy is properly employed, permanent suppression of ovarian function and damage rarely occur.

In 1939 I2 reported the case of a young woman who, intensely irradiated over the pelvic area at 4 years of age, nonetheless menstruated at 12 years and now, at the age of 17 1/2 years, continues to have regular periods. Commenting on this case, Dr. George L. Streeter3 of the Carnegie Institute of Embryology states:

"I believe the factor involved in your case is the principle that the more primordial

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