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Article
July 18, 1931

THE INCIDENCE OF EMBOLISM IN TREATMENT OF VARICOSE VEINS WITH SCLEROSING SOLUTIONS: REPORT OF A FATALITY

JAMA. 1931;97(3):177-178. doi:10.1001/jama.1931.27310030004010e

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Abstract

The occurrence of embolism following the injection of varicose veins with sclerosing solutions has always been greatly feared, although actual experience has shown it to be a most rare phenomenon.

A search of the literature has revealed a total of only nineteen cases of embolism following injection in hundreds of thousands of cases. Of these, fourteen were fatal and five patients recovered. In the present paper I am reporting another case of fatal embolism, making the total twenty cases, with fifteen fatalities and five recoveries. For the sake of completeness, I might add two cases that resulted in death from acute mercurial poisoning following the injection of a few cubic centimeters of 1 per cent corrosive mercuric chloride and red mercuric iodide, respectively. This brings the fatalities from the injection treatment up to seventeen, although the cases tabulated in group 2 may well be subtracted from this total, as in

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