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The term "uncomplicated duodenal ulcer" implies the absence of perforation, deep penetration, hemorrhage or gastric retention. The treatment of uncomplicated duodenal ulcer is a problem which is encountered so frequently that it constitutes a challenge to the ingenuity of the medical profession. This problem becomes even more important during wartime, when the incidence of duodenal ulcer increases. Great confusion regarding treatment has arisen because of the number and variety of therapeutic methods which are perennially finding their way into medical literature. Many of these so-called improved methods live a short period and die the natural death of fads, but some members of the medical profession go on applying them even after their sponsors have discontinued their use. Certain fundamental principles pertaining to peptic ulcer are not used sufficiently in the evaluation and treatment of this disease. Too often the local lesion is remembered and the patient who harbors the disease
SMITH LA, RIVERS AB. THE TREATMENT OF UNCOMPLICATED DUODENAL ULCER. JAMA. 1943;122(4):209–212. doi:10.1001/jama.1943.02840210001001