December 22, 1928


Author Affiliations


JAMA. 1928;91(25):1937-1941. doi:10.1001/jama.1928.02700250001001

The vomiting of pregnancy is a self-limiting disease, characterized by vomiting of a greater or less degree, in some instances so severe that death ensues before the system reacts to this complication.

The symptoms vary from a feeling of fulness in the abdomen and heartburn to vomiting persistently. Observation shows that the conditions associated with the vomiting are different from those of other vomiting. Here an individual, apparently well, with little or no prodromal syndromes, vomits. This vomiting is not associated with any of the usual clinical precursors of vomiting. There is no colic, gas pain, intestinal obstruction, previous operative work or anesthesia. As far as can be seen there should not be any vomiting. The apparent ease with which this vomiting is produced in the normal person gives one the impression that here is an opportunity to study the mechanism of vomiting, with the fewest complications possible. In an

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