A hundred years ago, Bright1 first showed the frequent association of dropsy, albuminuria and diseased kidneys. Since then there have been many advances in histologic technic. The kidneys have been studied intensively both in health and in disease, and yet an exact relationship has not been established between the formation of edema and the presence of albuminuria and structural abnormalities of the kidney. Newer methods of study have broadened the conception concerning these and other closely allied factors, so that the problems of nephritis are now regarded as both renal and extrarenal. These facts led Volhard and Fahr2 in 1914 to assemble the known clinical, laboratory and pathologic data in order to reclassify the various types of so-called renal disease. We here present a series of such cases in which edema was present and discuss suitable methods of treatment.
TYPES OF CASES STUDIED
In order that we might
BANNICK EG, KEITH NM. THE TREATMENT OF NEPHRITIS AND NEPHROSIS WITH EDEMA. JAMA. 1928;91(25):1944-1952. doi:10.1001/jama.1928.02700250008003