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Article
December 22, 1928

ISOLATION OF SUPRARENAL CORTICAL HORMONE

JAMA. 1928;91(25):2013-2014. doi:10.1001/jama.1928.02700250077033

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Abstract

To the Editor:  —In an editorial on the hormone of the suprarenal cortex (The Journal, November 3, p. 1376) credit is given to Hartman and his associates for the successful isolation of this substance. The editorial omits to take notice of my publication (Klin. Wchnschr. 7:1124 [June 10] 1928) in which the isolation of the hormone has been described already. I proposed "interrenin" as the name of this substance. The method of isolation which I used was extraction of the suprarenals with two-tenths normal hydrochloric acid and precipitation with sodium chloride. The alcoholic solution of the precipitate was reprecipitated several times until the active substance became protein free. The method published subsequently by Hartman in the September issue of the American Journal of Physiology is essentially the same as the one I had applied, which would suggest that his "cortin" is identical with "interrenin." My paper on interrenin had

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