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Medical research in the Dutch East Indies dates from 1629, when Jacobus Bontius was appointed doctor, apothecary and surgical supervisor. Bontius described beriberi, particularly the dry form, clearly and recognized syphilis and yaws. Flu lists the works of Bontius and other pioneers. Only after the middle of the nineteenth century, however, as a result largely of the stimulus of Pasteur, Patrick Manson and Laveran, was the study of disease in the Dutch East Indies placed on a scientific basis. In 1887 a pathologic and anatomic laboratory was established with Christiaan Eijkman as director. In 1891 a Pasteur institute was opened. Flu traces the close connection in early days of scientific research with the medical services. Vaccination was introduced in Java as early as 1802. In 1910 an independent civil medical service was established, which deals particularly with public health. The monograph gives a short sketch of the development and achievements
Koninklijke Akademie van Wetenschappen (Amsterdam). Internationale Circumpacifische Onderzoek Commissie (I. C. O.—Commissie). The History and Present State of Scientific Medical Research in the Dutch East Indies.. JAMA. 1931;97(6):413. doi:10.1001/jama.1931.02730060051032