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January 26, 1929

TRICHOMONAS VAGINALIS, DONNÉPRELIMINARY REPORT ON AN EXPERIMENTAL AND CLINICAL STUDY

JAMA. 1929;92(4):306-308. doi:10.1001/jama.1929.02700300030007
Abstract

Our purpose in this report is to record the results of observations that we have made on Trichomonas vaginalis during six months. It is hoped that our observations may stimulate others to investigate this parasite.

Donné,1 in 1837, observed that a flagellate parasite is present in certain vaginal secretions. This organism has been found by more recent observers in a rather high percentage of persistent abnormal vaginal discharges. (Hausmann, 40 per cent; Hoehne, 28 per cent; Witte, 40 per cent; Hegner,2 50 per cent, and Schmid and Kamniker,3 69.9 per cent.) Nevertheless, Trichomonas vaginalis remains a mystery. Its life history has never been worked out. How does it survive under unfavorable conditions? Does it multiply only by simple cell division or is there some type of sexual reproduction? Does it form spores? How do so many women become infected with this parasite? Brumpt4 found this organism in

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