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October 23, 1943

Regional Analgesia for Intra-Abdominal Surgery With Special Reference to Amethocaine Hydrochloride

JAMA. 1943;123(8):516. doi:10.1001/jama.1943.02840430068029

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This book was written to increase the interest of surgeons and anesthetists in the use of regional methods of anesthesia in England. It is an excellent presentation of the value of anethaine (amethocaine hydrochloride, or what is known in the United States as pontocaine hydrochloride) as an agent for producing prolonged anesthesia. The method of preparing the solution, its mixture with epinephrine and the equipment that is used are all described. Supplementary narcosis, intravenous administration of omnopon (pantopon) and the use of oxygen and anesthesia by inhalation and by use of barbiturates are discussed. Thoracic nerve block is described, as is also splanchnic block, especially the posterior method of Kappis; infiltration of lines of incision and infiltration for suprapubic drainage as well as for other purposes are described. The toxic effects and prophylaxis in relation to amethocaine hydrochloride are described. General operative technic is discussed as well as cooperation between

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