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To the Editor:—
In line with the article on "Vitamin Deficiency by Interference" in The Journal, September 18, page 151, it is interesting to note another evidence of this action. In attempts to prevent coccidiosis in chickens, it was shown (Holmes, C. E.; Deobold, H. J., and Herrick, C. A.: Sulfur and Rickets, Poultry Science17:136, 1938. Diseases of Poultry, edited by H. E. Biester and Louis Devries, Iowa State College Press, 1943, p. 755) that, when 2 to 5 per cent of sulfur was included in a ration in which the sole source of vitamin D was cod liver oil, rickets developed. Apparently the sulfur made the vitamin D of the cod liver oil unavailable for absorption.
Kaplan MM. VITAMIN DEFICIENCY BY INTERFERENCE. JAMA. 1943;123(10):655. doi:10.1001/jama.1943.02840450057029