Acute diarrhea is defined as lasting less than 14 days and can lead to significant morbidity and mortality. In the United States, approximately 179 million cases of acute gastroenteritis, including 47.8 million cases of food-borne illness, occur each year.1,2Clostridium difficile infections are the most common cause of diarrhea-associated mortality but are not addressed in this guideline.
Acree M, Davis AM. Acute Diarrheal Infections in Adults. JAMA. 2017;318(10):957–958. doi:10.1001/jama.2017.8485