February 19, 1944


Author Affiliations

A. U. S.

Instructor in Pharmacology, New York Medical College, Flower and Fifth Avenue Hospitals.

JAMA. 1944;124(8):528. doi:10.1001/jama.1944.02850080056026

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To the Editor:—  In the January 1 issue of The Journal there appeared an article by Dr. Johan T. Peters entitled "Easy and Accurate Method for Determination of Blood Sulfonamides from One Drop of Blood from the Finger Tip." The author quotes extensively our paper on the same subject (Determination of sulfanilamide and Its Derivatives in Blood, Am. J. Clin. Path., Tech. Supp. 6:22 [March] 1942) and, in the main, concurs with our findings and suggestions.On page 32, Dr. Peters states that "Churg's method was tried, which, compared with its predecessors, has many advantages. The method using sulfanilamide standards requires up to now, according to the description, 1 cc. of blood and has therefore to be considered as a macro method, as are all methods which use more than one drop of blood." The author then proposes in his micro modification for determination of "free" sulfanilamide only the

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