It is rather remarkable that, of all the infectious diseases of childhood, pertussis, comparatively speaking, has received the least attention from boards of health.1 This is indeed unfortunate in view of the large number of yearly deaths from that disease.2 Perhaps much of the apparent lack of interest on the behalf of health boards is due to skepticism of the reliability of early diagnosis, the lack of any generally accepted effective plan of therapy, and the failure of parents to carry out strict quarantine.
There are few diseases that have had so many different methods of treatment recommended for them as is true of pertussis.3 In view of this unfortunate state of affairs, I felt that I might derive some value from a comparative study of the more commonly used therapeutic measures. In addition, I thought it wise to try to ascertain the reliability of early diagnostic
McGEE WA. PERTUSSISITS EARLY DIAGNOSIS AND RECTAL ETHER TREATMENT. JAMA. 1931;97(13):922–926. doi:10.1001/jama.1931.02730130026008