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Article
April 15, 1944

VAGINAL SMEARS IN CARCINOMA OF UTERUS

JAMA. 1944;124(16):1136. doi:10.1001/jama.1944.02850160042014
Abstract

The death rate from carcinoma of the female genital tract, according to Dublin,1 is approximately 32,000 per year in the United States; of this figure four fifths, or 26,000, of the deaths annually are due to cancer of the uterus. This rate has remained practically constant during the past twenty-five years. This is tragic, since early diagnosis and modern treatment produce a high percentage of cures in carcinoma both of the fundus of the uterus and of the cervix. Papanicolaou and Traut2 point out that the present difficulty in early diagnosis is our great dependence on the subjective symptoms of the disease, to bring the patient to the physician. By the time the patient becomes sufficiently aware of discomfort to seek help, the disease is far advanced. Even when the patient is seen early in the course of the disease, the technic for making a positive diagnosis is

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