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April 15, 1944

Pancreatitis aguda: Etiologia—patogenia

JAMA. 1944;124(16):1162. doi:10.1001/jama.1944.02850160068039

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An excellent monograph on the etiology, pathogenesis and evolution of acute pancreatitis. What is classically known on the disease is well analyzed, and the experimental contributions of the author to the subject are numerous and well conducted. It is emphasized that the fundamental lesion is pancreatic necrosis. It has been postulated that this lesion can be produced by mechanical agents, circulatory and neurovascular causes, effect of bile and autodigestion. The author is inclined to think that all these actions precede or follow the fundamental cause, infection, while he considers that hypersensitiveness as a cause of acute pancreatitis in man has not been sufficiently proved. The illustrations are reproductions of photographs of gross and microscopic specimens. The index contains 219 references.

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