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To the Editor:—
The controversy between the advocates of intravenous and intramuscular quinine is a long one. However, we believe that the indications for intravenous quinine in falciparum malaria are clearly defined. It is recognized that intravenous quinine given improperly is a dangerous procedure. Not only are the cautions emphasized but the indications for intravenous quinine are clearly stated in the paper in question. Further, the senior author has himself administered well over one thousand doses of quinine intravenously to patients seriously ill with falciparum malaria and has experienced no ill effects which could be attributable to the use of quinine by vein.
Most H. ESTIVOAUTUMNAL MALARIA-Reply. JAMA. 1944;125(2):169. doi:10.1001/jama.1944.02850200076027