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June 3, 1944


Author Affiliations

President-Elect, American Medical Association

JAMA. 1944;125(5):326-327. doi:10.1001/jama.1944.02850230006003

My interest in the subject of drug therapy has been again aroused by the following possibly dangerous incident. I asked my intern to prescribe tincture of nux vomica for a patient who was leaving the hospital and who was to have the prescription filled in his home town 150 miles from Chicago. The intern wrote the following prescription: "[unk]: Tr. Nux Vomica oz. 6 Sig. 1 teaspoonful in 1/2 glass of water 3 times a day." The standard dose is 0.5 to 2 cc. A teaspoon holds 4 to 7 cc.

Several years ago I had a similar experience. I asked one of my fellows in urology to prescribe quinine sulfate for a child and to make a palatable mixture. He told me frankly that he had no idea how to prescribe quinine sulfate so as to make it palatable. When I questioned him about the instruction he had received

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