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Article
June 3, 1944

HUMAN DANDERAN IMPORTANT CAUSE OF INFANTILE ECZEMA

Author Affiliations

LOUISVILLE, KY.

From the Departments of Medicine and of Bacteriology and Immunology of the University of Louisville School of Medicine.

JAMA. 1944;125(5):350-351. doi:10.1001/jama.1944.02850230030008
Abstract

In previous reports evidence has been presented demonstrating the existence of an allergen in human dander, human hair from the scalp (probably including adherent dander) and in seborrheic eczema scales.1 The allergen was detected by means of skin reactions in certain patients with eczema. In 9 of 11 adults with atopic eczema urticarial reactions were obtained to scratch tests. In all 9 cases reagins were demonstrated by local passive transfer. In 8 of 12 infants and young children with eczema, eczematous reactions (redness, swelling, papulation, scaling) were obtained to patch tests (fig. 1). Negative controls were carried out with both types of test. In the case of the patch tests 23 noneczematous children, including 8 newborn infants, 9 other nonatopic children and 6 atopic noneczematous children, were tested. Twenty-two gave negative tests; 1 gave a moderately positive test. The etiologic significance of the urticarial reactions in the adults has

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