In a previous study of secondary anemia in pregnancy,1 it was found that approximately 50 per cent of the 200 maternity ward patients examined were anemic (erythrocyte counts below 3.5 million per cubic millimeter). An interesting feature of this study was the fact that, of forty-eight patients with a very severe grade of anemia during pregnancy (below three million cells), twenty-eight (58 per cent) improved within forty-eight hours after delivery.
It also disclosed that, of twenty-three patients manifesting a deficiency of red corpuscles with a hemoglobin varying between 45 and 76 per cent, twenty had practically completely recovered within six months after delivery. This recovery, occurring without any special therapeutic measures, suggested a further investigation in order to determine whether the recovery was merely accidental or a phenomenon to be generally expected.
Patients manifesting an anemia (counts below four million per cubic millimeter) in the sixth month of pregnancy
BLAND PB, GOLDSTEIN L. ANEMIA IN PREGNANCY WITH RECOVERYREPORT OF FIFTY CASES. JAMA. 1929;93(8):582–583. doi:10.1001/jama.1929.02710080008004