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December 16, 1944

Current Comment

JAMA. 1944;126(16):1031-1032. doi:10.1001/jama.1944.02850510039012

EFFECT OF AMPHETAMINE SULFATE ON PHYSICAL AND PSYCHIC PERFORMANCE  In Alwall's experiments1 large groups of soldiers were thoroughly fatigued by two or three nights of marching and exercises during the intervening one or two days, with little opportunity to sleep. In the course of the experiment the men marched 125 kilometers over a partly swampy ground with the temperature of the air being about 41 F. The men slept on an average three and one-fifth hours in the course of the entire experiment. On the termination of the fatigue exercises some of the men were given tablets containing 20 mg. of amphetamine sulfate, while others were given placebo tablets. Two and one-half hours later both groups were made to run 3 kilometers. Compared with the initial record established by the two groups just before they were subjected to the fatigue experiment, the postfatigue 3 kilometers

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