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December 23, 1944

PERSISTENCE OF VIRUS EXCRETION IN THE STOOLS OF POLIOMYELITIS PATIENTS

Author Affiliations

NEW HAVEN, CONN.

From the Section of Preventive Medicine, Yale University School of Medicine.

JAMA. 1944;126(17):1061-1062. doi:10.1001/jama.1944.02850520003002
Abstract

It is now an established fact that many patients with acute poliomyelitis excrete virus in their stools, but little is known of the duration of excretion of virus in fecal material beyond the first four weeks of the disease. The literature up to 1940 has been summarized in two papers by Vignec, Paul and Trask.1 An example of long persistence of the virus was reported in 1939 by Lépine and his associates,2 who demonstrated it in the stools of a child forty-one, seventy-four and possibly one hundred and twenty-three days after the abortive disease. Since 1940 two late isolations have been reported: one by Howitt, Buss and Shaffrath3 fifty days, and another by Wenner and Casey4 fortyfive days after the onset of poliomyelitis. Piszczek and his associates5 recovered virus from the stools of a healthy contact who had been exposed one and two months before

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