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The purpose of the investigation was to determine whether there had been any change in the incidence of rickets during wartime. A total of 5,283 children between the ages of 3 months and 18 months were examined. They were selected from twenty-three centers in the British Isles. The authors point out the great difficulty in the clinical diagnosis of mild rickets and also emphasize the fact that the radiologic diagnosis may often be in doubt. Of the 5,283 children, 106 were found to have radiologic evidence of rickets. In the children from 3 to 6 months of age the incidence was 2.5 per cent, between 6 months and a year 4 per cent, and practically none beyond this age. The clinical diagnosis of rickets showed great variability in different centers, being nil in some and as high as 61 per cent in others. The correlation between the clinical and the
Report on the Incidence of Rickets in War-Time. JAMA. 1945;127(8):493. doi:10.1001/jama.1945.02860080065028