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October 24, 1936

Foreign Letters

JAMA. 1936;107(17):1397-1402. doi:10.1001/jama.1936.02770430047020

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LONDON  (From Our Regular Correspondent)Sept. 8, 1936.

New Test for Estimating the Toxicity of Mineral Oils  The Manchester Committee on Cancer has just issued its report for 1935. Dr. C. C. Twort, director of the Cancer Research Laboratories, states that since the publication of the last report a new test has been devised for assessing the toxicity of mineral oils. Having found a simple method by which the approximate carcinogenicity of a mineral oil could be rapidly ascertained—by examination of its refractive—they investigated how the animal cells reacted to oils and this brought the new test to light. The test shows not only the probable carcinogenicity of an oil but also its probable power of causing dermatitis. It is performed by injecting a few drops of oil into an animal and recovering it for examination as to its physical characteristics. The basic principle of the test is that if

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