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November 7, 1936

TUBERCULOSIS AND CANCER

Author Affiliations

Ingleside, Neb.

JAMA. 1936;107(19):1560-1561. doi:10.1001/jama.1936.92770450003011a
Abstract

A consideration of the interrelation of tuberculosis and cancer presents a mass of contradictory observations. It is generally agreed that tumor cachexia as a nonspecific process will favor the development of tuberculosis, reactivate an old focus or accelerate the course of the disease. However, difference in the age incidence of the two diseases offers little opportunity to exercise such an influence.

That tuberculosis favors the development of cancer is supported by no less an authority than Ewing.1 In such malignant processes as the leukemias, lymphosarcomas, carcinoma of the lung and epithelioma on a subsoil of lupus vulgaris, it seems highly probable to Ewing that a tuberculous process is often the excitant. Along the same trend is l'Esperance's work on Hodgkin's disease as an atypical form of tuberculosis. Experimentally, Cherry2 has found a greater incidence in mice tumors concurrently inoculated with tubercle bacilli. With the exceptions

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