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The protean manifestations of the allergic state and the apparent infinitude of substances to which the human being may become sensitized have made us more conscious of the importance of knowledge in this field. Reports of new agents as sensitizers are encountered with increasing frequency. Recently a starch-splitting enzyme has been shown to be the causative agent in untoward gastro-intestinal symptoms following its administration. Certain constipation correctives of plant origin produce similar results. Many of these events cannot be foreseen. When products already marketed and of known composition are concerned, much needless inconvenience and not infrequently even dangerous reactions may be avoided by investigation previous to use. The more adequate labeling of these materials will prevent much unnecessary distress. No group of individuals is more aware of its environment, is more careful of its food, its drugs, its very milieu, than those who are allergic. Unless forewarned by their physicians
MASKED ALLERGENS. JAMA. 1936;107(19):1563-1564. doi:10.1001/jama.1936.02770450047016