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Trinitrotoluene has toxicity of a low order, but its manufacture and handling are not without risk to the health of the workers concerned. This series of studies raises a number of questions with respect to these hazards and brings their answers up to date by means of observations on animals and on man. The long debated question as to whether or not pure TNT is less dangerous to handle than an impure product is raised but not answered. This interim report is essential to all physicians concerned with the industrial hygiene of high explosives.
Experimental Studies on the Toxicity and Potential Dangers of Trinitrotoluene (TNT). JAMA. 1945;128(4):317. doi:10.1001/jama.1945.02860210073032