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June 2, 1945

POSITIVE PRESSURE RESPIRATION IN THE TREATMENT OF IRRITANT PULMONARY EDEMA DUE TO CHLORINE GAS POISONING

Author Affiliations

New York

From the Departments of Pediatrics and Medicine, Columbia University College of Physicians and Surgeons, and the Presbyterian Hospital.

JAMA. 1945;128(5):359. doi:10.1001/jama.1945.92860220004010a
Abstract

The development of positive pressure respiration by Barach and Eckmanl in the United States and by Poulton2 in England made possible a specialized form of inhalational therapy for bronchial asthma, laryngotracheal obstruction and acute pulmonary edema. The physiologic effects of pressure breathing, the results of its continuous application clinically and various methods of administration have been described previously3.

In cases of irritant pulmonary edema in which a continued exudation of serum from the capillaries into the alveoli takes place, despite rest and oxygen therapy, drainage through the respiratory passageway is impeded and bronchopneumonia and death may result. The administration of positive pressure to combat edema of the lungs produced by gas poisoning was suggested by Barach, Martin and Eckman4 in 1938 in a paper dealing with the therapeutic advantages of positive pressure in the treatment of clinical pulmonary edema. Mention was there made of a case of edema

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