Other Articles
December 12, 1936


Author Affiliations

San Francisco. Professor of Pharmacology, Stanford University School of Medicine.

JAMA. 1936;107(24):1985-1986. doi:10.1001/jama.1936.02770500051023

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


To the Editor:—  The advisability of using insoluble bismuth compounds in antisyphilitic treatment is periodically brought up for discussion by medical societies, clinics and individual physicians. A general interest in this matter may justify a summary of my views, which have been given on occasion extemporaneously. My views are based on the results of experimental and clinical studies over a period of years of several bismuth compounds in our department and in the literature. The very extensive data of the literature, including most of ours, may be found in a recent compilation by Forst of Munich, probably the most complete and best, single, up-to-date summary of the pharmacologic and clinical actions of bismuth (Handb. d. exper. Pharmakol.3:2249-2730 [part 4] 1935):The use of insoluble bismuth compounds in antisyphilitic treatment has been considerably favored, although this usage represents a curious contradiction in pharmacologic principles. The inconsistency is impressive when

First Page Preview View Large
First page PDF preview
First page PDF preview