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This book contains a reprint of two papers by John Snow, together with a biographic memoir by B. W. Richardson, M.D., and an introduction by Wade Hampton Frost, M.D., professor of epidemiology at the Johns Hopkins School of Hygiene and Public Health. Dr. Frost gives an interpretative introduction orienting the present-day reader with respect to the significance of Dr. Snow's contribution. Dr. Snow's two papers, on the Mode of Communication of Cholera and on Continuous Molecular Changes, more particularly in their relation to epidemic diseases, published in 1855 and 1853 respectively, are classics in epidemiology. His views on the mode of spread of cholera were confirmed in detail following the discovery of the specific cholera germ by Koch in 1883. The discussion of the chemistry of the blood of cholera patients and the effect of intravenous injections of saline solution in this disease, given on pages 11 to 13, are
Snow on Cholera, Being a Reprint of Two Papers. JAMA. 1937;108(5):421. doi:10.1001/jama.1937.02780050077036