The feeling that there is a definite trend toward the use of iodine in the treatment of toxic thyroid disease prompts the present discussion. It is to be presumed that there has been no appreciable decrease in the number of cases of diffuse toxic goiter and of nodular toxic goiter during the past six or seven years, yet the number of patients who have been submitting to thyroidectomy has markedly decreased. Furthermore, many who finally come to surgery have suffered from their disease for a longer period than was the case a few years ago. Many of these individuals have been given iodine in one form or another as part of their treatment. In a considerable number of instances they not only have become poor surgical risks but have an increased morbidity element which lengthens both the preoperative and the convalescent period.
It has been pointed out many times in
WETHERELL FS, GROAT WA. THE USE OF IODINE IN TOXIC GOITERS. JAMA. 1937;108(7):547-548. doi:10.1001/jama.1937.02780070031009