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February 27, 1937

THE SIGNIFICANCE OF SEROLOGIC TYPES AMONG MENINGOCOCCI

Author Affiliations

Senior Bacteriologist, National Institute of Health, United States Public Health Service WASHINGTON, D. C.

JAMA. 1937;108(9):692-696. doi:10.1001/jama.1937.02780090004002
Abstract

Meningococci form a single species, well defined, the members of which fall into broad serologic groups. The recognition of serologic differences by Dopter,1 Arkwright,2 Lieberknecht,3 Trautmann and Fromme4 and Elser and Huntoon5 in 1909 paved the way for the intensive work that followed and resulted in the classifications of meningococci into serologic types, which were reported during 1915-1918. At this time it was generally recognized that there were two main groups, which overlapped to some extent. They were called 1 and 2 by the English workers and A and B by the French. By absorption of agglutinins these were further divided by Gordon and Murray6 into four types, 1 becoming I and III, 2 becoming II and IV. French workers7 found two other groups, C and D, which were uncommon. Meanwhile other classifications had been developed elsewhere, including the bacteriotropin classification of Evans,

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