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November 17, 1945


JAMA. 1945;129(12):825. doi:10.1001/jama.1945.02860460049022

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To the Editor:—  A review of the article by Draeger and Pijoan on Treatment of Impetigo Contagiosa with Sulfathiazole in an Alcoholic Plastic Vehicle (The Journal, August 11, p. 1096) fails to reveal any mention of a control series of treatment with the vehicle minus the sulfathiazole. This a serious defect. Clinicians have recognized for decades the feasibility of successful treatment of impetigo contagiosa by occlusive dressings alone. It is important to have the authors indicate in a supplementary report the results in impetigo contagiosa of application of their alcoholic plastic vehicle without sulfathiazole.On the basis of insufficient clinical study, liquid provinyl acetate dressing inhibits growth of pus forming bacteria on the skin surface and in superficial injuries. Application of 55 per cent ethyl alcohol is also known to be a deterrent to bacterial growth. Its equivalent was the major volume of the alcoholic plastic vehicle of Draeger and

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