[Skip to Content]
[Skip to Content Landing]
Other Articles
December 1, 1945

ELECTROENCEPHALOGRAPHIC FINDINGS IN CENTRAL NERVOUS SYSTEM SYPHILISBEFORE AND AFTER TREATMENT WITH PENICILLIN

Author Affiliations

DURHAM, N. C.

From the Division of Dermatology and Syphilology, Department of Medicine, and from the Departments of Physiology and Neuropsychiatry. Duke University Hospital and School of Medicine.

JAMA. 1945;129(14):938-939. doi:10.1001/jama.1945.02860480018005
Abstract

Several authors1 have published reports on the cerebral electroactivity of patients with syphilis of the central nervous system. They agree that no correlation exists between the degree of abnormality of the electroencephalographic pattern and the type, the severity or the duration of the disorder. In the majority of the cases a definitely but nonspecifically abnormal electroencephalogram, or an electroencephalogram on the borderline between normal and abnormal, is found. However, enough patients with various types of neurosyphilitic disorders present electroencephalographic records "within normal limits" to detach from this procedure any immediate diagnostic significance.

After fever treatment has been completed, the abnormal cerebral electroactivity of neurosyphilitic patients often returns to normal or at least improves greatly. The changes of a previously abnormal pattern to normal seem to be correlated with the therapeutic success. Patients whose pathologic process is arrested by the fever but who retain residual symptomatology also retain many of

First Page Preview View Large
First page PDF preview
First page PDF preview
×