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April 24, 1937

CARCINOMA OF STOMACH IN A CURED CASE OF ADDISON-BIERMER'S (PERNICIOUS) ANEMIA

Author Affiliations

Attending Physician, Beth Israel Hospital; Clinical Professor of Medicine, New York University College of Medicine; Associate Physician, Beth Israel Hospital and Metropolitan Hospital; Associate Cardiologist, Beth Israel Hospital, and Instructor in Medicine, New York Medical College NEW YORK

JAMA. 1937;108(17):1398-1400. doi:10.1001/jama.1937.02780170016005
Abstract

Whereas a great number of cases have been reported of Addison-Biermer's (pernicious) anemia associated with cancer, in the preliver era as well as since the institution of liver treatment for this condition, the literature contains very few reports of authentic cases in which all the symptoms of anemia had disappeared, following which cancer of the stomach developed. In view of this rarity we are reporting a case in which a male patient developed Addison-Biermer's anemia in 1927, was completely cured by liver treatment, and recently developed cancer of the stomach.

REPORT OF CASE  J. K., a man, aged 63, married but without children, seen in March 1924, complained of indefinite gastric symptoms. A thorough gastro-intestinal roentgen examination at the time was negative. Examination of the stomach contents showed an absence of free acidity, a low total acidity and no lactic acid. The gastric symptoms were attributed to an unexplained achlorhydria.

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