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May 1, 1937

Foreign Letters

JAMA. 1937;108(18):1551-1555. doi:10.1001/jama.1937.02780180075021

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Abstract

LONDON  (From Our Regular Correspondent)April 3, 1937.

The Value of Irradiation in Malignant Disease  At the Royal Society of Medicine, Mr. Sampson Handley read a paper on the value of preoperation and postoperative irradiation in malignant disease. He could not draw any sharp line between radiation by x-rays and radiation by radium, though he thought the latter more effective in quality and subject to fewer drawbacks; but each method had its field. Mr. Handley mentioned three cases in which, subsequent to removal of internal abdominal malignant growths, nodular lumps appeared in the abdominal scar itself. Since radium can destroy massive implantation recurrences, it would a fortiori, if applied just after operation, destroy the microscopic cancer cells which are the seeds of recurrence. For this purpose Mr. Handley considered high voltage x-rays as effective as radium and more convenient. The facts of implantation recurrence alone provided a wide field for

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