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This is a careful study of anesthetic complications, with special emphasis on the effect of preliminary narcotic medication on the incidence of pulmonary complications. Three groups of cases are studied, a series of more than 3,000 cases occurring in the years 1921 to 1925, "prior to the introduction of basal narcosis," a series of more than 3,000 cases occurring in the years 1931 to 1935, "when basal narcosis was well established," and a series of more than 1,500 personal cases. While there is interesting and helpful discussion of all kinds of anesthetic complications, main interest is always on pulmonary complications and the effect thereon of preliminary narcosis. The crux of the whole matter is contained in the accompanying table.
The number of these cases is sufficiently large to make the figures of value, and the variation in results is sufficiently great to indicate clearly an increased incidence of pulmonary complications
On the Incidence of Anæsthetic Complications and Their Relation to Basal Narcosis. JAMA. 1937;109(8):614. doi:10.1001/jama.1937.02780340070033