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September 11, 1937

Cytologie du liquide céphalo-rachidien normal chez l'homme: Monographie critique et pratique

JAMA. 1937;109(11):899. doi:10.1001/jama.1937.02780370065033

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In this well written monograph the author discusses the morphology, physiologic significance and methods of counting the cells in the cerebrospinal fluid. To the small and large mononuclear cells normally considered to be present in the spinal fluid Jessen adds polygonal cells, which exist in various numbers, often up to 5,026 per cubic millimeter. These cells were not previously identified because they were considered to be products of degeneration. The author believes that the cerebrospinal fluid is principally a secretion of the choroid plexus and that the cells are probably of histiogenic origin. The normal cell count is up to 5 per cubic millimeter but there is a constitutional variation in the number of cells found. Some people have consistently low cell counts (from 0.1 to 0.2 per cubic millimeter) while others may have from 4 to 6 cells per cubic millimeter. The literature is thoroughly covered and there is

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