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One of us recently had the opportunity of studying the technic of the insulin shock treatment of schizophrenia under the guidance of Dr. Manfred Sakel of Vienna. During this teaching demonstration it was observed that there were some patients who frequently failed to arouse from coma after the feeding of sucrose solution by stomach tube. We often waited well over an hour after tube feeding before resorting to intravenous injection of dextrose, which promptly and invariably restored the patients to consciousness. Since starting this form of therapy at the Rochester State Hospital, March 1, 1937, we have had the same difficulty. Four of the first nine patients treated frequently required intravenous injection of dextrose because of failure to arouse after stomach feedings of sucrose solution.
For convenience we have had our feeding solution prepared in 8 ounce (240 cc.) bottles, with concentrations varying according to the size of the dosage of insulin.
Hunt RC, Feldman H. INTERRUPTION OF INSULIN SHOCK THERAPY. JAMA. 1937;109(14):1119-1120. doi:10.1001/jama.1937.92780400001009