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The author points out that frontal hyperostosis is accompanied by more or less constant symptoms. Adiposity is slow in developing and while finally most pronounced at the shoulders and hips, the nuchal region and the abdomen occasionally also become involved. Polyphagia and polydipsia become troublesome manifestations. Muscular asthenia may or may not be the cause of static disorders. The patient also has disturbed sleep, which may culminate in protracted insomnia and states of nocturnal agitation. There are also disorders in urination and often visual disturbances. The syndrome seems to be occasioned by disturbances in the infundibular and tuber cinereal regions, which in a few cases could.be verified. The triad of symptoms characteristic of Morgagni's syndrome are (1) frontal hyperostosis (main symptom), observed in 40 per cent of women during or following the menopause, (2) virilism, including masculine hirsutism and masculine features of the face, and (3) adiposity. The syndrome is
Veröffentlichungen aus der Konstitutions- und Wehrpathologie. JAMA. 1937;109(17):1392. doi:10.1001/jama.1937.02780430070045