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To the Editor:—
Regarding your review entitled "Pneumothorax from Experimental Overinflation of Lung" of my address before the fourth Federative International Congress of Anatomists at Milan, Italy, which appeared on page 959 of The Journal of September 18, I wish to record my satisfaction with the manner in which my results have been presented.Since the original paper was published I have found histologic evidence which confirms my former supposition that air from the overinflated region of the lung was leaking into the sheaths of the pulmonic arteries and veins through minute ruptures in the bases of those alveoli which overlie these sheaths. When a suspension of fine carmine grains in hot gelatin is injected into the previously overinflated part of the cat's lung, immediately after the experimental production of pneumothorax and massive collapse, through the catheter used for the air injection (which was allowed to remain in its former
Macklin CC. "PNEUMOTHORAX FROM EXPERIMENTAL OVERINFLATION OF THE LUNG". JAMA. 1937;109(18):1470-1471. doi:10.1001/jama.1937.02780440060026