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November 20, 1937

K. ycheniyu o ganglionevromakh tsentralnoy nervnoysistemy

JAMA. 1937;109(21):1750. doi:10.1001/jama.1937.02780470072029

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Abstract

Antonov presents a critical study of forty-six cases of so-called ganglioneuromas of the central nervous system collected from universal literature, together with a detailed histologic study of his own two cases. He concludes that evidence adduced in favor of the ganglionic nature of the large cells in cases of ganglioneuromas of the central nervous system cited, based on the morphology of the nucleus, the presence of the nucleolus and the size of the cells, is inadequate, since the same morphologic criteria hold true in the case of the large glial cells. The sole presence of "typical" ganglionic cells containing Nissl bodies and neurofibrils does not determine the nature of the neoplasm, since ganglionic cells as well as the neurofibrils are characterized by remarkable persistence and may remain preserved as preexisting cells and fibers in the case of a growing glioma. In order to prove that the typical ganglionic cells are

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