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December 11, 1937

Une forme cérébrale de la cholestérinose généralisée (type particulier de lipipose à cholestérine)

JAMA. 1937;109(24):2014. doi:10.1001/jama.1937.02780500070037

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This is the most recent monograph on cholesterol lipodosis. In the introduction it is stated that Ludwig Pick and Emil Epstein classify the diseases of lipoid metabolism into three groups which have as a common character deposits of lipids and fatty substances and which have a special characteristic determined lipid. These are the kerasine or cerebroside of Gaucher's disease, the phosphatide of Niemann-Pick's disease, and the cholesterol lipodosis characterized by the presence of cholesterol and its esters. This includes Schüller-Christian's disease. The authors also speak of a fourth group including progressive lipodystrophy, adiposogenital dystrophy and hypophysial obesity. The first chapter is a discussion of the actually known lipodoses. The second discusses the clinical facts of this disorder and the importance of the familial aspect in this entity. The third chapter deals with the anatomic and histopathologic study of the somatic and nervous lesions. The fourth chapter takes up the biochemical

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