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December 18, 1937

"RELATION OF NICOTINIC ACID TO HUMAN PELLAGRA"

Author Affiliations

Duke University, Durham, N. C.

JAMA. 1937;109(25):2086. doi:10.1001/jama.1937.02780510060022

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Abstract

To the Editor:—  May I call your attention to an error which occurred in The Journal, October 9, page 1203, in an editorial comment on "Relation of Nicotinic Acid to Human Pellagra." The statement referred to is as follows: "Chittenden and Underhill... using diets similar to those associated with human pellagra, were able to produce experimental blacktongue in dogs. They demonstrated that this disease was similar to, if not identical with, human pellagra. Conditions were thus provided for assaying experimentally the various fractions obtained during efforts to concentrate and identify the antipellagra dietary factor."Reference to the original publications by Chittenden and Underhill and Underhill and Mendel shows that they produced a blacktongue in dogs on a diet containing an abundance of red meat and yeast. Both of these substances will prevent and cure pellagra and the Goldberger type of blacktongue. There have been no assays on pellagra curative material

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