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January 8, 1938

THE METRAZOL CONTROVERSY

JAMA. 1938;110(2):144-145. doi:10.1001/jama.1938.02790020058025

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Abstract

To the Editor:—  In reply to, and as a companion communication to the one presented to The Journal Oct. 30, 1937, page 1470, by Dr. Joseph Wortis, the following points ought likewise to be presented to the medical profession:1. In answer to the question posited to him as to who originated the convulsive therapy of schizophrenia, Dr. L. von Meduna published the article "Die Bedeutung des epileptischen Anfalls in der Insulin- und Cardiazolbehandlung der Schizophrenie" (The Significance of the Convulsive Reaction During Insulin and Metrazol Therapy of Schizophrenia), Psychiatrisch-Neurologische Wochenschrift39:331 (July 24) 1937. I had the pleasure of assisting in the translation of this article, which will appear in the Journal of Nervous and Mental Disease in a short time, and I quote here a few brief passages:"On the basis of the publications of Sakel, and later of Dussik and Sakel, we conclude that:

  1. The

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